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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STON2 All Species: 22.42
Human Site: S115 Identified Species: 44.85
UniProt: Q8WXE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WXE9 NP_149095.2 905 101165 S115 D T P W A S T S P P H Q E T A
Chimpanzee Pan troglodytes XP_001135210 905 101144 S115 D T P W A S T S P P H Q E T A
Rhesus Macaque Macaca mulatta XP_001105584 896 100013 S115 D T P W A S T S P P H Q E T A
Dog Lupus familis XP_864856 735 82747
Cat Felis silvestris
Mouse Mus musculus Q8BZ60 895 99593 S115 D T P W S S T S P P H K E T A
Rat Rattus norvegicus NP_001129346 895 99472 S115 D T P W S N T S A P H K E T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505629 865 95494 S115 E S W T G T L S T H Q E A A P
Chicken Gallus gallus XP_421302 887 99388 V115 P P T H P Q A V S P P K A P S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028915 859 96510 V114 Q S E E Q S S V S M G A S S C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24212 1262 137751 S144 S Q L D E T S S E L L G R I P
Honey Bee Apis mellifera XP_396872 1188 129859 T285 G A T L I T T T T Q E N P F V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795059 1041 114812 S169 V S S T P L K S V V P E K G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 31.4 N.A. 86.1 85.8 N.A. 68 69.8 N.A. 48.5 N.A. 23.6 24.7 N.A. 25.5
Protein Similarity: 100 99.6 98 49.5 N.A. 90 89.7 N.A. 76.8 79.8 N.A. 61.7 N.A. 38.7 40 N.A. 44.6
P-Site Identity: 100 100 100 0 N.A. 86.6 73.3 N.A. 6.6 6.6 N.A. 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 0 N.A. 100 93.3 N.A. 33.3 20 N.A. 26.6 N.A. 20 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 25 0 9 0 9 0 0 9 17 9 42 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 42 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 9 9 9 0 0 0 9 0 9 17 42 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 9 0 0 0 9 0 0 0 0 0 9 9 0 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 9 42 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 9 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 25 9 0 0 % K
% Leu: 0 0 9 9 0 9 9 0 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % N
% Pro: 9 9 42 0 17 0 0 0 34 50 17 0 9 9 17 % P
% Gln: 9 9 0 0 9 9 0 0 0 9 9 25 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 9 25 9 0 17 42 17 67 17 0 0 0 9 9 9 % S
% Thr: 0 42 17 17 0 25 50 9 17 0 0 0 0 42 0 % T
% Val: 9 0 0 0 0 0 0 17 9 9 0 0 0 0 9 % V
% Trp: 0 0 9 42 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _